What Are GLP-1 Medications?
GLP-1 receptor agonists (like semaglutide and tirzepatide) mimic a natural hormone that reduces appetite, slows stomach emptying, and helps regulate blood sugar. Originally developed for type 2 diabetes, they've become the most effective prescription weight loss treatments available.
How Much Weight Can You Expect to Lose?
Clinical trials show average weight loss of 15-17% of body weight over 68 weeks with injectable semaglutide, and 13.6% with the oral pill version. In real-world Clyne data, patients lose an average of 29.3 lbs in six months when combining medication with diet and exercise.
Who Is Eligible?
GLP-1 medications are prescribed for adults with a BMI of 30+ (obese) or 27+ (overweight) with at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol. A Clyne provider can evaluate your eligibility with a same-day online consultation.
What Side Effects Should You Know About?
The most common side effects are gastrointestinal: nausea (40% of patients initially), constipation, and diarrhea. These typically improve within 4-6 weeks. Eating smaller, protein-rich meals and staying well-hydrated significantly reduce symptoms.
How to Get Started
Complete an online health questionnaire, have a same-day consultation with a licensed provider, and receive your medication shipped directly to your door. Your Clyne dashboard tracks your progress, connects your wearable data, and gives you 24/7 access to your care team.
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This content is reviewed by Clyne®'s editorial team and grounded in published clinical evidence. Citations are listed at the end of each piece. Clyne® Concierge translates the science; your physician makes all clinical decisions. We never fabricate trial data, patient stories, or outcomes.
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